Table 1 List of bladder cancer single nucleotide polymorphisms (SNPs) used to create the weighted genetic risk score.

From: Interaction between blood pressure and genetic risk score for bladder cancer, and risk of urothelial carcinoma in men

SNP

Gene

Effect allele

Other allele

EAF (%)

Odds ratio

ln (Odds ratio)

rs1014971

CBX6/APOBEC3A

T

C

65.6

1.18

0.165514

rs10775480

SLC14A2

T

C

45.5

1.13

0.122218

rs10936599

ACTRT3/MYNN/TERC/LRRC34

C

T

74.2

1.15

0.139762

rs11892031

UGT1A8/UGT1A10

A

C

91.9

1.17

0.157004

rs1495741

NAT2

A

G

72.7

1.13

0.122218

rs17674580

SLC14A1

T

C

36.9

1.17

0.157004

rs2294008

JRK/PSCA

T

C

42.4

1.13

0.122218

rs2736098a

TERT

A

G

31.3

1.16

0.14842

rs401681

TERT/CLPTM1L

C

T

57.8

1.12

0.113329

rs4907479

NR

A

G

27.8

1.13

0.122218

rs6104690

C20orf187/ LOC339593

A

G

42.4

1.07

0.067659

rs62185668

JAG1

A

C

25.8

1.19

0.173953

rs710521

TP63

A

G

70.2

1.18

0.165514

rs7238033

SLC14A1

C

T

45.5

1.2

0.182322

rs798766

TMEM129/TACC3/FGFR3

T

C

79.3

1.2

0.182322

rs8102137

CCNE1

C

T

28.8

1.13

0.122218

rs907611

LSP

A

G

33.3

1.15

0.139762

rs9642880

MYC/BC042052/CASC11

T

G

40.9

1.21

0.19062

  1. SNP, single nucleotide polymorphism; EAF, effect allele frequency; ln, natural log.
  2. SNP information (except rs2736098 [TERT]) was obtained externally from genome-wide association studies of BC reviewed in: de Maturana, E. L. et al. Bladder cancer genetic susceptibility. A systematic review. Bladder Cancer. 4, 215–226. https://doi.org/10.3233/blc-170159 (2018)7.
  3. aSNP information on rs2736098 (TERT) was obtained from the GWAS catalog: Institute, N. H. G. R. (2008). www.ebi.ac.uk/gwas/home.
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