Table 2 Bivariate correlation analysis of PC1-Clin and PC2-Clin versus the PCs of the other datasets.

From: A multi-marker integrative analysis reveals benefits and risks of bariatric surgery

  

PC1-Clin

Adiposity, insulin resistance and systemic inflammation

PC2-Clin

Hepatic cholesterol metabolism

r(s)

n

p

r(s)

n

p

Plasma oxidative stress markers

PC1-Ox

Nutritional status

0.471

71

< 0.001

PC2-Ox

Global oxidative balance

− 0.453

71

< 0.001

− 0.263

71

0.027

PC3-Ox

Lipid-associated oxidative stress

0.328

71

0.005

0.293

71

0.013

PC4-Ox

Liver-related plasma redox status

0.281

71

0.018

PC5-Ox

Glutathione metabolism

− 0.236

71

0.048

1H NMR serum metabolic markers

PC2-Met

One-carbon metabolism

− 0.502

33

0.003

PC4-Met

Glucose metabolism

0.584

33

< 0.001

Plasma peptide mediators

PC1-Pep

Tissue reparative processes vs inflammatory macrophage infiltration

− 0.339

43

0.026

PC2-Pep

Angiogenic processes

0.467

43

0.002

PC4-Pep

Adipose tissue function and insulin sensitivity

− 0.462

43

0.002

RBC membrane fatty acids

PC1-MFA

ω-6/ω-3 FA competition

− 0.337

86

0.002

PC4-MFA

Free radical stress

0.257

86

0.017

PC5-MFA

SFA and ω-6 FA metabolism

0.237

86

0.028

  1. Only significant correlations are shown.