Table 2 Bivariate correlation analysis of PC1-Clin and PC2-Clin versus the PCs of the other datasets.
From: A multi-marker integrative analysis reveals benefits and risks of bariatric surgery
PC1-Clin Adiposity, insulin resistance and systemic inflammation | PC2-Clin Hepatic cholesterol metabolism | ||||||
|---|---|---|---|---|---|---|---|
r(s) | n | p | r(s) | n | p | ||
Plasma oxidative stress markers | |||||||
PC1-Ox | Nutritional status | – | – | – | 0.471 | 71 | < 0.001 |
PC2-Ox | Global oxidative balance | − 0.453 | 71 | < 0.001 | − 0.263 | 71 | 0.027 |
PC3-Ox | Lipid-associated oxidative stress | 0.328 | 71 | 0.005 | 0.293 | 71 | 0.013 |
PC4-Ox | Liver-related plasma redox status | – | – | – | 0.281 | 71 | 0.018 |
PC5-Ox | Glutathione metabolism | – | – | – | − 0.236 | 71 | 0.048 |
1H NMR serum metabolic markers | |||||||
PC2-Met | One-carbon metabolism | – | – | – | − 0.502 | 33 | 0.003 |
PC4-Met | Glucose metabolism | 0.584 | 33 | < 0.001 | – | – | – |
Plasma peptide mediators | |||||||
PC1-Pep | Tissue reparative processes vs inflammatory macrophage infiltration | – | – | – | − 0.339 | 43 | 0.026 |
PC2-Pep | Angiogenic processes | – | – | – | 0.467 | 43 | 0.002 |
PC4-Pep | Adipose tissue function and insulin sensitivity | − 0.462 | 43 | 0.002 | – | – | – |
RBC membrane fatty acids | |||||||
PC1-MFA | ω-6/ω-3 FA competition | – | – | – | − 0.337 | 86 | 0.002 |
PC4-MFA | Free radical stress | – | – | – | 0.257 | 86 | 0.017 |
PC5-MFA | SFA and ω-6 FA metabolism | 0.237 | 86 | 0.028 | – | – | – |