Figure 3
From: EZH2 regulates oncomiR-200c and EMT markers in esophageal squamous cell carcinomas
EZH2 silencing led to downregulation of miR-200c and mesenchymal genes, and upregulation of epithelial genes expression in ESCC lines. miR-200c expression decreased nearly − 2.04 log2 fold change in YM-1 cells and − 3.78 in KYSE-30 cells, moreover it caused a decrease in mRNA level of ZEB2, Fibronectin, N-cadherin and Vimentin in ESCC lines while the epithelial genes E-Cadherin and Occludin were upregulated.
