Table 2 Association with saliva microbiota alpha diversity of potential influential factors. Multivariate models are presented for each sample: full sample, dietary sub-sample, and periodontal disease subsample. All models are adjusted for multiple testing and resultant Q values are given. Full sample (n = 679): in a multivariate model adjusting for all other variables listed (not including diet or periodontal disease), factors associated with saliva microbiota alpha diversity were age (Q = 0.004, Shannon Index; Q = 0.003, Simpson Index) and frailty (Q = 0.004, Observed; Q = 0.002, Shannon Index; Q = 0.003, Simpson Index). In the dietary subsample (n = 582), the associations demonstrated in the full sample were robust to adjustment for diet; factors associated with alpha diversity were age (Q = 0.006, Shannon Index; Q = 0.003, Simpson Index) and frailty (Q = 0.003, Observed; Q = 0.002, Shannon Index; Q = 0.003, Simpson Index). In the periodontal disease subsample (n = 134), alpha diversity was associated with frailty (Q = 0.002, Observed; Q = 0.04, Shannon).

From: Influential factors of saliva microbiota composition