Figure 1
From: Characteristics of intermediate age-related macular degeneration with hyperreflective foci

A representative case of a 71-year-old woman with intermediate age-related macular degeneration (AMD) colocalizing with hyperreflective foci (HRF) in the left eye and type-3 macular neovascularization (MNV) in right eye. (A) Color fundus photography of the left eye at the initial appearance demonstrates drusenoid pigment epithelial detachment (DPED) surrounded by reticular pseudodrusen in the macular area. (B) At 7 months after initial presentation, color fundus photography of the left eye demonstrates the development of intraretinal hemorrhage in the macular area. (C) A horizontal scan through the fovea by spectral-domain optical coherence tomography (SD-OCT) in the left eye at the initial appearance shows HRF (black arrow) near the protrusion of DPED. (D) A horizontal SD-OCT scan through the fovea of the left eye at 7 months shows the presence of intraretinal fluid (black arrowhead) and increased HRF (black arrow). (E) Fluorescein angiography and (F) indocyanine angiography of the left eye at 7 months shows a hot spot (yellow circle) that is consistent with type-3 MNV.