Figure 6

Genetic decision rules for predicting future worsening of disability for PwMS. These rules indicate how the MErf ensemble model combines allele dosages from a set of influential genetic variants amongst the 28 candidates SNPs to make prediction decisions regarding future disability. Each rule indicates the expected EDSS transition time conditional on the effects of genetic variants, MS disease course (MSTYPE), and previous disability histories (EDSSPREV). Only rules for the first four visits have been shown.