Figure 4
From: MiR-27a as a diagnostic biomarker and potential therapeutic target in systemic sclerosis
Predicted targets of miR-27a in the EMT pathway. miR-27a could interact with and target multiple gene transcripts contributing to the EMT signaling pathway which eventually results in the differentiation of fibroblasts into myofibroblasts; these cells are responsible for the development of fibrosis which is a key feature of SSc.
