Table 2 Characteristics and IgG seroprevalence in community-dwelling adults in Germany (14,781 RKI-SOEP study participants with valid dried blood spot specimens, sampled predominantly in October–November 2020).

From: Nationally representative results on SARS-CoV-2 seroprevalence and testing in Germany at the end of 2020

 

Total

N sero-positive (row %, unweighted)

Proportion of seropositives, corrected for specificity = 0.997 and initial test sensitivity = 0.811

Estimate of cumulative seroprevalence since the beginning of the pandemic corrected for specificity = 0.997 and sensitivity that includes antibody decay = 0.616

Seropositive cases with unnotified infection (according to self-report)

N

N (row %)

Row % (95% CI)

% of seropositives (95% CI)

Total 18–99 years

14,781

192 (1.3%)

1.3% (0.9–1.7)

1.7% (1.2–2.3)

48% (37–59)

Total 18–69 years

12,324

167 (1.4%)

1.4% (1.0–2.0)

1.9% (1.3–2.7)

45% (34–57)

Sex

Women

7938

82 (1.0%)

1.1% (0.6–1.7)

1.4% (0.8–2.2)

49% (32–67)

Men

6843

110 (1.6%)

1.5% (1.0–2.1)

1.9% (1.3–2.8)

46% (31–62)

Age group

18–34 years

2741

46 (1.7%)

2.0% (1.1–3.5)

2.6% (1.4–4.7)

43% (26–61)

35–49 years

3484

35 (1.0%)

1.2% (0.5–2.4)

1.6% (0.7–3.2)

47% (22–73)

50–64 years

4846

68 (1.4%)

1.3% (0.7–2.1)

1.7% (0.9–2.8)

44% (26–64)

65–79 years

3055

39 (1.3%)

0.6% (0.2–1.3)

0.8% (0.3–1.7)

68% (40–87)

80–99 years

655

4 (0.6%)

0.2% (− 0.2 to 1.7)

0.3% (− 0.2 to 2.2)

100%

Household composition

18–59 years

 1 person

1168

10 (0.9%)

1.0% (0.2–2.9)

1.3% (0.3–3.8)

31% (6.1–75)

 2–4 persons, incl. children

3494

38 (1.1%)

1.3% (0.6–2.5)

1.7% (0.8–3.2)

35% (16–61)

 2–4 persons, no children

3410

52 (1.5%)

1.1% (0.6–1.9)

1.5% (0.8–2.5)

48% (28–68)

 > 4 persons, incl. children

1168

24 (2.1%)

4.4% (2.0–9.0)

5.8% (2.7–12)

54% (20–85)

 > 4 persons, no children

112

2 (1.8%)

0.5% (− 0.2 to 3.2)

0.6% (− 0.2 to 4.2)

0%

60+ years

 1 person

1165

7 (0.6%)

0.2% (− 0.2 to 1.2)

0.3% (− 0.2 to 1.6)

72% (24–95)

 > 1 person

3842

54 (1.4%)

1.0% (0.5–1.7)

1.3% (0.7–2.2)

57% (37–76)

School education

Low

2662

32 (1.2%)

1.5% (0.7–2.7)

1.9% (0.9–3.5)

52% (26–77)

Medium

5057

64 (1.3%)

1.1% (0.6–1.8)

1.4% (0.8–2.4)

51% (30–71)

High

6177

82 (1.3%)

1.1% (0.7–1.7)

1.4% (0.9–2.2)

45% (28–62)

Incidence stratum (district level)a

High incidence (Cluster A)

2979

47 (1.6%)

2.1% (1.0–3.9)

2.7% (1.3–5.1)

46% (27–65)

Average incidence (Cluster B)

8497

117 (1.4%)

1.1% (0.7–1.6)

1.4% (0.9–2.1)

44% (30–60)

Late second wave (Cluster C)

1658

18 (1.1%)

1.3% (0.4–3.2)

1.7% (0.5–4.3)

66% (34–88)

Low incidence (Cluster D)

1643

10 (0.6%)

0.5% (− 0.0 to 1.8)

0.7% (− 0.0 to 2.4)

65% (25–92)

Regional socioeconomic deprivation (district level)

Low deprivation

3915

65 (1.7%)

1.4% (0.9–2.3)

1.9% (1.1–3.0)

45% (27–64)

Medium deprivation

8790

103 (1.2%)

1.1% (0.6–1.8)

1.4% (0.8–2.3)

47% (32–63)

High deprivation

2072

24 (1.2%)

1.7% (0.7–3.5)

2.3% (1.0–4.6)

57% (29–81)

  1. Numbers do not add up to total due to missing values in single variables (available-case analysis). All percentages are population-weighted unless otherwise specified.
  2. aDistrict incidence strata according to pattern of weekly sequence of district SARS-CoV-2 incidence (notified cases), see Supplement 3.