Table 2 The characterized of studies that included TNF-α analysis.

From: Influence of Vitamin A supplementation on inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials

Author, year

Country

Sample size

Mean age

Sex

Dose (mg)

Duration of treatment (weeks)

Type

TNF-α change in intervention and placebo group a

S. E. Cox (2006)

England

99

21

F

10,000

15

Vit A

0.24 vs. − 0.18

Mahdieh Abbasalizad Farhangi (2013)

Iran

50

38

F

25,000

16

Retinyl palmitate

− 0.02 vs. − 0.01

Shaikh M. Ahmad (2009)

Bangladesh

36

25

M

240,000

56

Vit A

− 0.2 vs. − 3

Sama Bitarafan (2019)

Iran

79

35

M/F

25,000

24

Retinyl palmitate

61.17 vs 110.59

Tingting Cai (2019)

Bangladesh

30

54

M

50,000

44

Vit A

− 4.17 vs. − 3.23

  1. Summary of clinical trials on the effects of vitamin A supplementation on inflammatory biomarker (TNF-α). TNF-α tumour necrosis factor-α, M male, F female, a Changes in cytokine concentrations are presented by common units for TNF-α (pg/mL).