Figure 3 | Scientific Reports

Figure 3

From: Safety and efficacy of human polymerized hemoglobin on guinea pig resuscitation from hemorrhagic shock

Figure 3

Markers of kidney function after resuscitation. Stored blood and PolyhHb groups indicate changes in kidney function compared to the fresh blood group, as observed by increased serum creatinine. However, the level of dysfunction could be transient since BUN and U Ngal, both kidney damage markers, did not change when compared to the fresh blood group. (A) Serum creatinine; (B) Blood urea nitrogen (BUN); (C) Urinary neutrophil gelatinase-associated lipocalin (U Ngal). Measurements were taken 24 h after resuscitation. *, p < 0.05 versus Fresh Blood. Statistical comparisons were completed using a one way—ANOVA; Tukey’s multiple comparison test.

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