Figure 4

Markers of cardiac injury. Stored blood caused a greater degree of cardiac injury compared to fresh blood, since cardiac troponin increased for stored blood. However, resuscitation with stored blood or PolyhHb did not cause remarkable changes in cardiac inflammation. (A) Interleukin-6 (IL-6); (B) Tumor necrosis factor alpha (TNFα); (C) Monocyte chemoattractant protein-1 (MCP-1); (D) Troponin; (E) C-reactive protein; (F) Atrial natriuretic peptide (ANP). Measurements were taken 24 h after resuscitation. *, p < 0.05 vs. Fresh Blood; †, p < 0.05 versus Stored Blood. Statistical comparisons were completed using a one way—ANOVA; Tukey’s multiple comparison test.