Figure 5
Systemic inflammation, splenic inflammation, and catecholamines. Neither PolyhHb or stored blood presented higher systemic inflammation compared to fresh blood (the gold standard for resuscitation). However, stored blood increased catecholamine levels compared to fresh blood and PolyhHb suggesting higher sympathetic activation after resuscitation. (A) Interleukin-6 (IL-6); (B) Chemokine ligand 1 (CXCL-1); (C) Interleukin-1(IL-10); (D) Splenic CXCL-1; (E) Norepinephrine; (F) Epinephrine. Measurements were taken 24 h after resuscitation. *, p < 0.05 versus Fresh Blood; †, p < 0.05 versus Stored Blood. Statistical comparisons were completed using a one way—ANOVA; Tukey’s multiple comparison test.
