Figure 10
From: Fexinidazole interferes with the growth and structural organization of Trypanosoma cruzi
Epimastigotes cell cycle in the presence of FEX for 72 h. (A) Histograms of control and treated parasites. Black and color lines indicate untreated and treated epimastigotes, respectively. (B) Percentage of parasites in G1, S, and G2/M. In the control group, most epimastigotes were in the G1 phase, followed by S and G2/M. From 10 µM, there was a lower number of parasites in G1 and a higher percentage in G2/M. This pattern became more pronounced at higher concentrations. The histograms are representative and the data are the average of two independent experiments (*p > 0.05; **p < 0.05; ***p < 0.001).
