Figure 8
From: Fexinidazole interferes with the growth and structural organization of Trypanosoma cruzi
Transmission electron microscopy of T. cruzi amastigotes in the presence of FEX for 72 h. (A) Non-treated amastigotes present the nucleus (n) with the condensed heterochromatin, a single branched mitochondrion (m), and a bar-shaped kinetoplast (k). (B) Five-hundred nanomolar did not promote ultrastructural modifications on amastigotes. (C, D) One micromolar caused Golgi disorganization (black arrow) and mitochondrial swelling (asterisk). (E, F) Amastigotes treated with 5 µM presented mitochondrial swelling (asterisk).
