Figure 1

Stratified Q–Q plot (A) and Fold-enrichment plot (B). Stratified Q–Q plot: Nominal versus empirical \({-\mathrm{log}}_{10}(\mathrm{p})\) values in CBMI as a function of significance of association with CAD at different levels. Fold-enrichment plot: Enrichment versus nominal \({-\mathrm{log}}_{10}(\mathrm{p})\) values for CBMI as a function of significance of the association with CAD.