Table 1 Pleiotropy assessed between CBMI and CAD by GPA method.

From: Identification of potentially common loci between childhood obesity and coronary artery disease using pleiotropic approaches

 

\({\uppi }_{00}\)

\({\uppi }_{10}\)

\({\uppi }_{01}\)

\({\uppi }_{11}\)

LRT

p-value

CBMI-CAD

0.857 (0.006)

0.048 (0.006)

0.090 (0.003)

0.005 (0.002)

79.352

5.2E−19

  1. The values in the brackets are standard errors of the estimates. The last two columns provide the LRT statistics and p-values of hypothesis testing. The \({\uppi }_{00}\) represents the proportion of the SNPs not associated with CBMI or CAD; \({\uppi }_{10}\) and \({\uppi }_{01}\) represent the proportion of the SNP associated with CBMI and CAD, respectively; \({\uppi }_{11}\) represents the proportion of the SNP associated with CBMI and CAD.
Back to article page