Table 1 Baseline characteristics of enrolled RA patients.

From: Baseline bony erosions and time-averaged DAS28 predict discontinuation of TNF inhibitors in rheumatoid arthritis

 

RA patients (N = 109)

Age (years)

52.0 [46.0; 63.0]

Female (n, %)

97 (89.0%)

Disease duration (years)

2.0 [1.0; 6.1]

BMI (kg/m2)

22.4 [20.5; 24.7]

Regular exercise (yes)

47 (43.1%)

Smoking

Nonsmoker

97 (89.0%)

Ex-smoker

6 (5.5%)

Current smoker

6 (5.5%)

Baseline Td joint (yes)

17 (15.6%)

Baseline swollen joint (yes)

22 (20.2%)

Baseline erosions of hands or feet

30 (27.5%)

Baseline JSN of hands or feet

39 (35.8%)

Medication

Methotrexate

92 (84.4%)

Hydroxychloroquine

5 (4.6%)

Sulfasalazine

1 (0.9%)

Leflunomide

2 (1.8%)

NSAIDs

92 (86.8%)

Glucocorticoid dose (mg/day, equivalent to prednisolone)

2.5 [2.0; 5.0]

Previous bDMARDs use history (yes)

13 (11.9%)

Adalimumab

6

Etanercept

4

Infliximab

3

Current TNFi

Adalimumab

48 (44.0%)

Etanercept

61 (56.0%)

Laboratory findings

CRP (mg/dL)

0.4 [0.3; 1.1]

ESR (mm/hr)

26.0 [13.0; 45.0]

RF positive

90 (82.6%)

ACPA positive

79 (72.5%)

PhGA (0–100)

22.0 [11.0; 36.0]

PtGA (0–100)

32.0 [13.0; 57.0]

Baseline DAS28

4.0 [3.2; 5.0]

Baseline HAQ

0.8 [0.4; 1.2]

  1. All data are presented as number (%) or median with interquartile range.
  2. RA rheumatoid arthritis, BMI body mass index, JSN joint space narrowing, NSAID nonsteroidal anti-inflammatory drug, bDMARDs biological disease-modifying antirheumatic drugs, TNFi tumor necrosis factor inhibitor, CRP C-reactive protein, ESR erythrocyte sedimentation rate, RF rheumatoid factor, ACPA anticitrullinated protein antibody, PhGA physician’s global assessment, PtGA patient’s global assessment, DAS28 disease activity score 28, HAQ health assessment questionnaire.