Figure 1 | Scientific Reports

Figure 1

From: Mohawk impedes angiofibrosis by preventing the differentiation of tendon stem/progenitor cells into myofibroblasts

Figure 1

Fibrovascular scarring in human tendinopathy. (A) Acta2, Col3a1, CD31, Angptl2 and Pdgfr gene expression profiling from GEO datasets of human tendinopathy and surrounding non-lesioned tissues (n523, Affymetrix platform, profile reference: GSM1310181). (B) Histological staining of diseased proximal biceps tendon sections or non-lesioned control tissues (n = 5). Scale bar, 50 μm. (C) Representative immunofluorescence images (n = 5) of human proximal biceps tendon sections stained for α-SMA/VEGFR2, CD31/Col3a1 or DAPi. Scale bars, 40 μm. D. Representative MKX expression in tendinopathy specimens from 2 two different patients. DAPI (blue), MKX (red). Scale bar, 40 µm.

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