Table 1 Participant Characteristics in CATHGEN discovery cohort and TECOS validation cohort.
From: Protein biomarkers of cardiac remodeling and inflammation associated with HFpEF and incident events
n | CATHGEN discovery cohort | TECOS validation cohort | ||||
|---|---|---|---|---|---|---|
Non-HF | HFpEF | p | Non-HF | HFpEF | p | |
88 | 88 | 79 | 30 | |||
Age (mean (SD)) | 53.1 (12.3) | 64.7 (11.3) | < 0.001 | 65.6 (8.5) | 64.5 (8.3) | NS |
Female, n (%) | 37 (42.0) | 38 (43.2) | NS | 16 (20.2) | 11 (36.7) | NS |
Non-white, n (%) | 21 (23.9) | 26 (29.5) | NS | 18 (22.8) | 7 (23.3) | NS |
BMI, kg/m2 (mean (SD)) | 29.2 (7.7) | 32.0 (8.5) | 0.02 | 31.8 (19.8) | 35.1 (6.8) | 0.03 |
SBP, mmHg (mean (SD)) | 138.3 (25.1) | 151.0 (29.7) | 0.003 | 132.7 (19.8) | 145.7 (17.4) | 0.002 |
Creatinine, mg/dL (mean (SD)) | 0.93 (0.21) | 1.38 (1.28) | 0.001 | 1.04 (0.29) | 1.1 (0.39) | NS |
Diabetes mellitus, n (%) | 11 (12.5) | 30 (34.1) | 0.001 | 79 (100) | 30 (100) | NA |
CAD, n (%) | 48 (54.5) | 46 (52.3) | NS | 74 (93.7) | 28 (93.3) | NS |
LVEF (mean (SD)) | 57.9 (7.7) | 57.3 (7.4) | NS | > 55 (0.0) | > 55 (0.0) | NA |
Atrial fibrillation, n (%) | 12 (13.6) | 20 (22.7) | 0.17 | 8 (10.01) | 5 (16.7) | NS |
