Figure 2
From: Development of the stria vascularis in the common marmoset, a primate model
Development of the marginal cells of the stria vascularis in the primate cochlea. (A and B) Expression of ATP1A1, BSND, and SLC12A2 in E101 cochlea. In the apical turn, no BSND expression is detected, whereas SLC12A2 expression can be observed (Bracket in A). In the basal turn, BSND expression can be detected along with SLC12A2 expression. ATP1A1 expression in the lateral wall of the epithelium of the cochlear duct is still broader than that of SLC12A2 (Bracket in B). (C–E) Expression of ATP1A1, BSND, and SLC12A2 in E109 cochlea. At E109, the BSND expression can be observed in the apical turns. The basolateral membrane of the marginal cells is relatively smooth (Arrowheads in C). In the basal turns of E109 cochlea, ATP1A1, BSND, and SLC12A2 are expressed in marginal cells. The basolateral membrane of the marginal cells is becoming more intricate compared to the apical turn (Arrows in E). (F and G) Expression of ATP1A1, BSND, and SLC12A2 in E115 cochlea. Expression of ATP1A1, BSND, and SLC12A2 are detected in marginal cells at this stage. The basolateral membrane of the marginal cells has been getting more complex from E109. (H and I) Expression of ATP1A1, BSND, and SLC12A2 in P0 cochlea. Expression patterns of ATP1A1, BSND, and SLC12A2 are similar to those at E115; hence this stage is morphologically similar to E115. The nuclei were counterstained with Hoechst (blue). Scale bar: 50 µm in A–C, 20 µm in D–I.
