Table 2 Differentially abundant lipids (microM) in the CF saliva versus controls.

From: Lipidomic alterations in human saliva from cystic fibrosis patients

Lipid subclass

q-value

p-value

Mean of controls

Mean of CF patients

Difference

ratio

Ceramides

Cer(d16:1/18:0)

0.000439

0.000163

0.0668

0.1047

0.0379

1.5671

Cer(d16:1/20:0)

0.000439

0.000163

0.0204

0.0341

0.0137

1.6683

Cer(d16:1/24:0)

0.000467

0.000202

0.0095

0.0144

0.0048

1.5084

Cer(d18:0/20:0)

0.001088

0.000606

0.1787

0.2429

0.0642

1.3593

Cer(d18:0/22:0)

0.00005

0.000003

0.1380

0.2593

0.1214

1.8790

Cer(d18:0/24:1)

0.00007

0.000013

0.0916

0.1575

0.0658

1.7189

Cer(d18:0/26:1)

0.001672

0.001035

0.0951

0.1393

0.0442

1.4646

Cer(d18:1/14:0)

0.000175

0.000043

0.0436

0.0816

0.0380

1.8714

Cer(d18:1/16:0)

0.00795

0.009347

0.0336

0.1307

0.0971

3.8934

Cer(d18:1/18:0)

0.005448

0.006026

0.0166

0.0285

0.0120

1.7218

Cer(d18:1/20:0)

0.003358

0.003325

0.0138

0,0321

0,0184

2.3367

Cer(d18:1/23:0)

0.001014

0.000502

0.0128

0.0310

0.0183

2.4288

Cer(d18:1/26:0)

0.002565

0.00195

0.0400

0.0611

0.0210

1.5254

Cer(d18:2/14:0)

0.00007

0.000012

0.0354

0.0665

0.0311

1.8778

Cer(d18:2/16:0)

0.003033

0.002627

0.0227

0.0331

0.0105

1.4627

Cer(d18:2/18:1)

0.005448

0.006069

0.0259

0.0374

0.0115

1.4462

Cer(d18:2/20:0)

0.001821

0.001239

0.0286

0.0477

0.0191

1.6698

Cer(d18:2/23:0)

0.003358

0.003202

0.0109

0.0184

0.0076

1.6952

Cer(d18:2/24:0)

0.002565

0.002063

0.0158

0.0274

0.0117

1.7405

Hexosylceramides

Hex2Cer(d18:1/26:0)

0.000617

0.000056

0.0053

0.0101

0.0048

1.8977

Hex3Cer(d18:1/16:0)

0.003421

0.001018

0.0361

0.0740

0.0379

2.0513

Hex3Cer(d18:1/24:1)

0.003421

0.001382

0.0263

0.0462

0.0199

1.7585

HexCer(d16:1/24:0)

0.005278

0.002794

0.0044

0.0080

0.0036

1.8063

HexCer(d18:1/14:0)

0.003421

0.000833

0.0053

0.0080

0.0027

1.5145

HexCer(d18:1/18:0)

0.003421

0.001

0.0124

0.0269

0.0145

2.1738

HexCer(d18:1/18:1)

0.005278

0.00285

0.0234

0.0314

0.0081

1.3452

HexCer(d18:1/20:0)

0.003421

0.001346

0.0247

0.0441

0.0194

1.7851

HexCer(d18:1/23:0)

0.000078

0.000004

0.0373

0.1169

0.0796

3.1340

HexCer(d18:1/24:0)

0.004155

0.00187

0.0378

0.0789

0.0411

2.0860

HexCer(d18:1/26:0)

0.001718

0.000232

0.0126

0.0384

0.0258

3.0469

HexCer(d18:1/26:1)

0.003421

0.001386

0.0124

0.0197

0.0073

1.5926

Diacylglycerols

DG-O(14:0_18:2)

0.001366

0.000239

0.3378

0.5254

0.1876

1.5554

DG(14:0_14:0)

0.000028

< 0.000001

0.0817

0.2158

0.1341

2.6410

DG(14:0_18:2)

0.007583

0.002208

0.2519

0.4087

0.1569

1.6225

DG(14:0_20:0)

0.001552

0.000316

0.2744

0.3530

0.0785

1.2864

DG(14:1_18:1)

0.007303

0.001914

0.2203

0,3038

0.0835

1.3790

DG(17:0_17:1)

0.000255

0.00003

0.2146

0.3034

0.0888

1.4138

DG(18:1_20:0)

0.000215

0.000019

0.5280

0.8065

0.2785

1.5275

DG(18:1_20:3)

0.005596

0.001304

0.3140

0.4858

0.1718

1.5471

DG(18:1_22:6)

0.000161

0.000009

0.9782

0.5458

− 0.4325

0.5580

DG(22:1_22:2)

0.00033

0.000048

0.2075

0.3406

0.1331

1.6414

Triacylglycerols

TG(14:0_38:5)

0.001562

0.000039

0.0310

0.0590

0.0280

1.9020

TG(18:1_31:0)

0.000052

 < 0.000001

0.8639

1.5270

0.6633

1.7676

TG(18:2_31:0)

 < 0.000001

 < 0.000001

0.6381

1.2510

0.6128

1.9605

TG(20:1_31:0)

0.000002

 < 0.000001

3.4890

6.9370

3.4480

1.9882

TG(20:3_32:1)

0.000192

0.000003

0.0434

0.0826

0.0392

1.9017

TG(20:4_36:4)

0.000769

0.000016

0.0251

0.0678

0.0427

2.7008

Cholesterol esters

CE(20:1)

0.000001

 < 0.000001

0.5129

0.8441

0.3312

1.6457

Lysophosphatidylcholine

lysoPC a C18:0

0.002285

0.000679

0.1503

0.2297

0,0795

1.5283

lysoPC a C18:2

0.006928

0.002744

0.1088

0.0693

− 0.0395

0.6367

lysoPC a C20:3

0.000041

0.000004

0.2124

0.0877

− 0.1247

0.4131

lysoPC a C20:4

0.001973

0.000391

0.0542

0.0350

− 0.0191

0.6466

Phosphatidylcholine

PC ae C44:5

0.008677

0.000232

0.0265

0.0389

0.0125

1.4718

Acylcarnitines

C0

0.000138

0.000012

2.8400

4.7560

1.9160

1.6746

C16

0.001126

0.000127

0.1323

0.2188

0.0865

1.6538

C16:2-OH

0.000002

 < 0.000001

0.1215

0.0890

− 0.0326

0.7322

C7-DC

 < 0.000001

 < 0.000001

0.5043

0.3682

− 0.1361

0.7301

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