Table 1 Cohort characteristics.
From: Associations between subcutaneous adipocyte hypertrophy and nonalcoholic fatty liver disease
All cases | Non-NASH | NASH | P | Controls | |
|---|---|---|---|---|---|
n = 32 | n = 12 | n = 20 | n = 15 | ||
Sex, male, n (%) | 17 (53.1) | 8 (66.7) | 9 (45) | 0.234 | 5 (33.3) |
Age, years, mean (± SD) | 55.2 (14.4) | 52.9 (16.5) | 56.5 (13.1) | 0.503 | 55.7 (10.3) |
BMI, kg/m2, mean (± SD) | 30.3 (4.6) | 27.9 (1.5) | 31.7 (5.3) | 0.019 | 26.2 (2.4) |
T2D (%) | 15 (46.9) | 2 (16.7) | 13 (65.0) | 0.008 | 0 (0) |
HOMA-IR, median (IQR) | 7.1 (5.1–10.9) | 4.7 (4.0–6.7) | 8.2 (6.9–13.2) | 0.008 | NA |
ALT U/L, mean (± SD) | 87.8 (51.5) | 75.6 (42.5) | 90.5 (54.1) | 0.446 | NA |
Fibrosis stage | |||||
No fibrosis, n (%) | 3 (9) | 1 (10) | 2 (9) | ||
Stage 1, n (%) | 11 (34) | 6 (60) | 5 (24) | ||
Stage 2, n (%) | 10 (31) | 3 (30) | 7 (33) | ||
Stage 3, n (%) | 6 (19) | 0 (0) | 6 (29) | ||
Stage 4, n (%) | 2 (6) | 0 (0) | 2 (9) | ||
Steatosis | |||||
Score 1, n (%) | 3 (9.4) | 2 (16.6) | 1 (5.0) | ||
Score 2, n (%) | 11 (34.4) | 5 (41.7) | 6 (30.0) | ||
Score 3, n (%) | 18 (56.3) | 5 (41.7) | 13 (65.0) | ||
Lobular inflammation | |||||
Grade 0, n (%) | 5 (15.6) | 5 (41.7) | 0 (0) | ||
Grade 1, n (%) | 21 (65.6) | 7 (58.3) | 14 (70.0) | ||
Grade 2, n (%) | 5 (15.6) | 0 (0) | 5 (25.0) | ||
Grade 3, n (%) | 1 (3.2) | 0 (0) | 1 (5.0) | ||
Hepatocyte ballooning | |||||
Grade 0, n (%) | 11 (34.4) | 11 (91.7) | 0 (0) | ||
Grade 1, n (%) | 13 (40.6) | 1 (8.3) | 12 (60.0) | ||
Grade 2, n (%) | 8 (25.0) | 0 (0) | 8 (40.0) | ||
