Figure 1 | Scientific Reports

Figure 1

From: Transcriptome profiling of colorectal tumors from patients with sepsis reveals an ethnic basis for viral infection risk and sepsis progression

Figure 1

Transcriptome profiling of Native Hawaiian and Japanese colorectal cancer-associated sepsis samples. (a) Experimental design. (b) Number of total differentially expressed genes in Native Hawaiian samples compared to Japanese. (c) Volcano plot of differentially expressed genes for Native Hawaiians vs Japanese (red indicates upregulated genes, and green downregulated genes with a fold change of > 1.5, < − 1.5 and false discovery rate < 0.05). (d) Heatmap showing significant up- and down-regulated differentially expressed genes in Native Hawaiians compared to Japanese involved in sepsis, septic shock, viral infection and colon adenocarcinoma. (e) Network of most enriched genes from heatmap in (d) generated in IPA and their associated canonical pathways (CP). Legend describes log2(FPKM) values.

Back to article page