Figure 2 | Scientific Reports

Figure 2

From: Transcriptome profiling of colorectal tumors from patients with sepsis reveals an ethnic basis for viral infection risk and sepsis progression

Figure 2

Top disease phenotypes, canonical pathways and predicted upstream regulators of differentially expressed genes in Native Hawaiians when compared to Japanese. (a) Number of up- and downregulated genes in most enriched disease phenotypes. Green bars are downregulated genes, red bars are upregulated genes. (b) Bubble plot indicating the top canonical pathways, where bubble size corresponds to number of genes enriched for corresponding pathway and color indicates z score. Orange bubbles indicate predicted activation and a positive z score, blue bubbles indicate predicted inhibition and a negative z score. Grey bubbles indicate no z score or a z score of 0. (c) Network of genes affected by predicted upstream regulators Lh, LARP1, and RICTOR, and their associated canonical pathways (CP). (d) Network of genes affected by YAP1 and associated CPs.

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