Table 3 Risks associated with the development of AFL (A) and dyspnoea (B) at 5 years.

From: Development of airflow limitation, dyspnoea, and both in the general population: the Nagahama study

(A)

RRb

Adjusted RRb

(B)

RRb

Adjusted RRb

Age ≥ 60 years

2.24 (1.84–2.74)

1.58 (1.40–1.79)

Age ≥ 60 years

1.41 (1.26–1.58)

1.22 (1.13–1.31)

Female

0.39 (0.33–0.47)

0.66 (0.57–0.77)

Female

1.07 (0.95–1.21)

1.19 (1.06–1.32)

Smoking status

  

Smoking history

  

Current vs. former

1.54 (1.20–1.97)

2.04 (1.45–2.87)

Current vs. former

1.41 (1.15–1.72)

1.79 (1.37–2.34)

Former vs. never

1.86 (1.51–2.29)

1.06 (0.76–1.48)

Former vs. never

0.82 (0.75–1.01)

0.93 (0.73–1.19)

BMI ≥ 25 kg/m2

0.77 (0.61–1.00)

0.76 (0.65–0.88)

BMI ≥ 25 kg/m2

1.39 (1.23–1.57)

1.21 (1.11–1.32)

Hypertension

1.31 (1.07–1.59)

1.08 (0.95–1.22)

Hypertension

1.38 (1.23–1.55)

1.14 (1.05–1.24)

Diabetes

1.08 (0.76–1.53)

0.82 (0.67–1.02)

Diabetes

1.13 (0.92–1.39)

0.99 (0.85–1.14)

Cardiovascular disease

1.19 (0.80–1.76)

0.95 (0.75–1.21)

Cardiovascular disease

1.79 (1.48–2.16)

1.43 (1.22–1.69)

%FEV1 < 80%

3.74 (2.96–4.73)

2.17 (1.77–2.67)

%FEV1 < 80%

1.27 (0.99–1.63)

1.15 (0.96–1.37)

FEV1/FVC < LLN

5.51 (3.98–7.63)

4.61 (3.00–7.06)

FEV1/FVC < LLN

0.77 (0.39–1.53)

0.96 (0.64–1.43)

SP-370 at follow-upa

2.28 (1.61–3.22)

1.58 (1.31–1.90)

SP-370 at follow-upa

1.08 (0.92–1.27)

1.03 (0.94–1.14)

  1. RR risk ratio, AFL airflow limitation, BMI body mass index, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, LLN lower limits of normal. aSpirometer used at follow-up. bRR (95% confidence interval).