Figure 3
Protein–protein pathway analysis illustrating significantly downregulated proteins in POTS. Protein–protein interaction analysis of 7 out of 11 upregulated proteins with association networks detected by STRING in POTS. In the network figures, each protein is represented by a colored node while protein–protein interaction and association are represented by a line. The strongest network interactions in POTS were particularly associated with a hypercoagulable state, inflammation, and enhanced cardiac contractility and hypertrophy. Complete names of proteins are found in Table 2.
