Table 1 Minimal inhibitory concentration (MIC) and minimal bactericidal inhibitory concentration (*MBC) monomeric quaternary ammonium salts (QAS) with different counterion (Me—methylcarbonates, Ac—acetates, Br—bromides) and aliphatic chain length (C12, C14, C16).
Strain | Compound | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (*MBC) of tested compounds [µM] | |||||||||
MeC12 | MeC14 | MeC16 | AcC12 | AcC14 | AcC16 | BrC12 | BrC14 | BrC16 | |
S. epidermidis ATCC 35984 | 320 *640 | 40 *40 | 40 *40 | 640 *640 | 160 *160 | 640 *640 | 640 *640 | 160 *160 | 640 *640 |
S. epidermidis B374 | 640 *160 | 80 *160 | 80 *160 | 320 *320 | 40 *40 | 40 *40 | 640 *640 | 640 * > 640 | 10 *10 |
S. epidermidis SI8 | 320 *640 | 40 *40 | 10 *10 | 640 *640 | 160 *160 | 10 *10 | 640 *640 | 160 *160 | 10 *10 |
S. aureus ATCC 6538 | 320 *640 | 80 *80 | 10 *10 | 1280 *1280 | 160 *160 | 80 *80 | 1280 *1280 | 320 *320 | 320 *320 |
S. aureus MRSA R98 | 640 *640 | 80 *80 | 40 *40 | 640 *640 | 160 *160 | 10 *10 | 640 *640 | 320 *320 | 320 *320 |
E. coli ATCC 11229 | 640 *640 | 320 *320 | 320 *320 | 1280 *1280 | 320 *320 | 80 *160 | 1280 *1280 | > 1280 * > 1280 | 640 *1280 |
E. coli H64 | 640 *640 | 80 *80 | 80 *80 | 1280 *1280 | 160 *160 | 160 *320 | 1280 *1280 | 320 *320 | 160 *160 |
P. aeruginosa ATCC 27853 | > 1280 * > 1280 | 1280 * > 1280 | > 1280 * > 1280 | > 1280 * > 1280 | 1280 * > 1280 | > 1280 * > 1280 | 1280 *1280 | 1280 *1280 | > 1280 * > 1280 |
P. aeruginosa PAO1 | > 1280 * > 1280 | > 1280 * > 1280 | > 1280 * > 1280 | > 1280 * > 1280 | > 1280 * > 1280 | > 1280 * > 1280 | > 1280 * > 1280 | > 1280 * > 1280 | > 1280 * > 1280 |
