Figure 2 | Scientific Reports

Figure 2

From: A practical spatial analysis method for elucidating the biological mechanisms of cancers with abdominal dissemination in vivo

Figure 2

(a) Preservation of spatial information in the sectioned slides. Magnetic resonance imaging (MRI) images [left: T2-weighted image (T2WI); right: T1-weighted image (T1WI)], sectioned organs, and macro images of hematoxylin and eosin (H&E)-stained section specimens from nude BALB/c mice with ES-2 ovarian cancer dissemination are shown. I Intestine, K kidney, L liver, P pancreas, S spleen. Scale bar: 2 mm. (b) Sequential MRI images [upper images: T2-weighted images (T2WIs); lower images: T1-weighted images (T1WIs)] and sectioned organs at the same anatomical level as the MRI images. Scale bar: 2 mm. (c) Comparison between the spatial information obtained using MRI and that obtained from the sectioned slides created using our method. A disseminated small nodule (inset, T) was visible in the sectioned slide. Scale bar: 2 mm.

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