Figure 1

Data quality control. (a) Overlapping BPC (base peak ion flow diagram) plots of all QC samples. The different color peak curves in the figure represent different QC samples. All QC samples in the figure have good overlapping plots, and the retention time of each QC sample and its corresponding peak corresponding intensity fluctuations are small, which indicates that the detection instrument is operating well during the sample detection and analysis. (b) Principal component analysis plot. The horizontal coordinate is the first principal component PC1, the vertical coordinate is the second principal component PC2, and the ellipse is the 95% confidence interval; each circle point represents a sample, and different colors represent different groups (green is QC sample, red is normal group, and blue is sepsis group). All three groups have good differentiation, and the high overlap of QC samples indicates the more stable testing instrument.