Table 1 Biological properties of hemp seed oil.

From: Comparing the extraction methods, chemical composition, phenolic contents and antioxidant activity of edible oils from Cannabis sativa and Silybum marianu seeds

Antioxidant/method; parameter

ORAC; 28.2 ± 6.19 (µmol TE/g)26

ABTS; 11.4 ± 2.08 (µmol TE/g)26, IC50 = 99.96 (µg/mL)29, IC50 = 66.6 (µg/mL)29

Chelating properties estimated by 2,2-bipyridyl reagent/assay; 10.5 ± 0.83 (EDTA mg/g)26

TCA; 0.44 ± 0.01(mg GAE/g)26, 2.45 ± 0.05 (mg CAE/100 g)24

DPPH; IC50 = 10.7 mg/mL, IC50 = 9.2 mg/mL29, EC50 = 8,7 µg24

Antimicrobial

Antibacterial activity against Bacillus cereus (Inhibition Zone Size 2.3 ± 0.6 mm), Bacillus subtilis subsp. Subtilis (2.3 ± 1.8 mm), Micrococcus luteus (3.3 ± 1.8 mm), Staphylococcus aureus subsp. aureus (3.0 ± 0.0 mm), Citrobacter freundii (2.3 ± 0.6 mm), Enterococcus faecalis (2.3 ± 0.6 mm), Escherichia coli (0.3 ± 0.6 mm), Salmonella enterica (3.0 ± 1.8 mm)10

Antifungal activity against Microsporum canis30

Anti-diabetes

Protection against atherosclerosis, reduce the level of LDL, increase the level of HDL31

Stimulation of blood platelet aggregation32

Anti-inflammatory

Reduction of bladder and bowel diseases9

Hemp seed extract rich in lignanamides (LnHS) significantly inhibits U-87 cancer cell proliferation29

  1. TE trolox equivalent, TCA total phenolic/antioxidant content, CAE caffeic acid equivalents, EDTA equivalent represents the chelating capacity, LDL low-density lipoprotein, HDL high-density lipoprotein, FRAP ferric ion reducing antioxidant parameter
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