Figure 1
From: Effect of benznidazole on cerebral microcirculation during acute Trypanosoma cruzi infection in mice
Characterization of the experimental model (Swiss Webster/Y strain). The following parameters were evaluated in a kinetic study: (A) parasitemia, (B) weight and (C) survivor. The parasitemia peak occurred at 8 dpi, and benznidazole treatment cleared parasitemia (A). T. cruzi infection induced body weight decrease in YNT group starting at 10 dpi, benznidazole treatment had no effect on this decrease (B). Benznidazole in both doses used impaired mortality (C). NI, non infected; Y, infected; NT, non treated; BZ, treated with benznidazole (100 mg); BZ/2, treated with benznidazole (50 mg); dpi, days post-infection.
