Table 3 The results for comparitive analysis on genera (pairwise comparisons). *Ref represents the reference/baseline group, Com represents the comparison group, Est and SE represent the estimated regression coefficient and its standard error, t represents the t statistic value, and Adj. P-value represents the FDR adjusted P-value.

From: Integrative web cloud computing and analytics using MiPair for design-based comparative analysis with paired microbiome data

Genus	Ref	Com	Est	SE	t	Adj. P-value
g_Bacteroides	Baseline	Week 2	0.772	0.198	3.898	0.001
g_Bacteroides	Baseline	Week 4	− 0.201	0.200	− 1.004	0.389
g_Coprococcus	Baseline	Week 2	1.876	0.468	4.006	0.001
g_Coprococcus	Baseline	Week 4	0.597	0.474	1.258	0.290
g_Blautia	Baseline	Week 2	− 0.938	0.483	− 1.942	0.111
g_Blautia	Baseline	Week 4	− 1.519	0.490	− 3.099	0.012
g_Coprobacillus	Baseline	Week 2	− 0.127	0.100	− 1.270	0.285
g_Coprobacillus	Baseline	Week 4	0.161	0.101	1.586	0.285
g_Lactobacillus	Baseline	Week 2	2.339	0.334	6.995	< 0.001
g_Lactobacillus	Baseline	Week 4	1.892	0.339	5.579	< 0.001
g_Enterococcus	Baseline	Week 2	− 0.765	0.375	− 2.038	0.098
g_Enterococcus	Baseline	Week 4	− 2.705	0.380	− 7.109	< 0.001
g_Staphylococcus	Baseline	Week 2	− 2.504	0.314	− 7.973	< 0.001
g_Staphylococcus	Baseline	Week 4	− 2.157	0.318	− 6.779	< 0.001
g_Bilophila	Baseline	Week 2	− 0.092	0.340	− 0.272	0.864
g_Bilophila	Baseline	Week 4	1.552	0.344	4.514	< 0.001
g_Oscillospira	Baseline	Week 2	0.104	0.320	0.325	0.863
g_Oscillospira	Baseline	Week 4	0.793	0.325	2.442	0.067
g_Ruminococcus	Baseline	Week 2	0.195	0.351	0.555	0.751
g_Ruminococcus	Baseline	Week 4	1.768	0.356	4.968	< 0.001
g_Clustridium	Baseline	Week 2	2.142	0.596	3.591	0.002
g_Clustridium	Baseline	Week 4	3.057	0.605	5.050	< 0.001
g_Pantoea	Baseline	Week 2	− 0.568	0.221	− 2.573	0.062
g_Pantoea	Baseline	Week 4	− 0.453	0.224	− 2.025	0.076
g_Trabulsiella	Baseline	Week 2	− 0.916	0.307	− 2.986	0.012
g_Trabulsiella	Baseline	Week 4	− 1.663	0.312	− 5.332	< 0.001
g_Klebsiella	Baseline	Week 2	− 1.379	0.348	− 3.968	0.001
g_Klebsiella	Baseline	Week 4	− 2.654	0.353	− 7.529	< 0.001
g_Prevotella	Baseline	Week 2	0.048	0.362	0.131	0.896
g_Prevotella	Baseline	Week 4	1.349	0.366	3.683	0.002

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