Table 2 Performance of CLEC3B-ECM1-IP10-SELL signature for comparison of clinical groups and TB treatment monitoring.

From: Plasma host protein signatures correlating with Mycobacterium tuberculosis activity prior to and during antituberculosis treatment

Purpose

Groups

AUC

SE

SP

CutOff

ACC

TN

TP

FN

FP

NPV

PPV

Clinical group comparisons

 

ATB vs HD

0.958

0.946

0.917

0.412

0.934

22

35

2

2

0.917

0.946

 

ATB vs TBI

0.929

0.892

0.913

0.536

0.9

21

33

4

2

0.84

0.943

 

HD vs TBI

0.741

0.565

0.958

0.564

0.766

23

13

10

1

0.697

0.929

Treatment monitoring

 

Fast vs Slow converters

0.87

0.833

0.84

0.272

0.838

21

10

2

4

0.913

0.714

  1. AUC area under the ROC curve, SE sensitivity, SP specificity, PPV positive predictive value, NPV negative predictive value, ACC accuracy.
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