Table 2 Data domain categories and descriptions.

From: Identifying myoglobin as a mediator of diabetic kidney disease: a machine learning-based cross-sectional study

Domain

Descriptions

Data type

Number of features

Demographics

Gender, age

Binary, numeric

2

Hospitalization characteristics

Hospitalization date, leave date, hospital day, admission department, discharge department

Date, numeric, integer

5

General information

Height, weight, BMI, mean SBP, SD SBP, max SBP, min SBP, mean DBP, SD DBP, max DBP, min DBP, mean HR, SD HR, max HR, min HR

Numeric

15

Laboratory tests

GHBA1C, fasting glucose, fasting insulin, fasting C-peptide, 120 min glucose , 120 min insulin, 120 min C-peptide, TC, TG, LDL-C, HDL-C, HDL-C/TC ratio, HGI, TyG index, TG/HDL ratio, HOMA-IR, HOMA-BETA, IGI, IGI/HOMA-IR, I/G 0 min, I/G 120 min, Gutt index, WBC, Hb, PLT, MCV, MCH, MCHC, Neu, Lym, Lym%, Neu%, CK, LDH, CK-MB, Mb, troponin, BNP, UMALB, BUN, Scr, UA, eGFR, C-reactive protein, hypersensitive C-reactive protein, NLR, PLR

Numeric, integer

47

Diagnoses

T2DM, hyperlipidemia, DKD, CKD, stages of CKD, renal anemia, renal bone disease, DR, stages of DR, DN, diabetic foot, CAD, heart failure, stages of heart failure, extremity arteriosclerosis, carotid atherosclerosis, renal artery stenosis and sclerosis, cerebral arteriosclerosis, retinal arteriosclerosis, acute MI, old MI, congestive heart failure, stroke, end-stage renal disease, sepsis, septicemia, HT, stages of HT, peptic ulcer, fatty liver disease, cirrhosis, viral hepatitis, chronic bronchitis, COPD, asthma, arrhythmia, atrial flutter and atrial fibrillation, pregnancy period, hyperthyroidism, hypothyroidism, hyperparathyroidism, hashimoto's thyroiditis, brain tumors, breast tumors, lung tumors, digestive system tumors, urinary system tumors, thyroid tumors, tumors of the male reproductive system, tumors of the female reproductive system, leukemia, lymphoma, metastasis, respiratory system infection, urinary system infection, rheumatoid or connective tissue disease, other cerebrovascular diseases or TIA, other liver diseases, HIV/AIDS, hemiplegia, Alzheimer’s disease, rhabdomyolysis, hemolysis, nephritis, infection, tumors

Numeric, binary

66

Medications

Diuretics, beta-blockers, calcium-channel blockers, ACE inhibitor, angiotensin-receptor blocker, vasodilators, statins, fibrates, other lipid-lowering agents, sulfonylureas, glinides, biguanides, thiazolidinediones, alpha-glucosidase inhibitors, DPP-4 inhibitor, SGLT-2 inhibitor, insulin, antihypertensive agents, lipid-lowering agents, hypoglycemic agents

Binary

20

Others

ACCI, FRS

Integer

2

  1. SBP systolic blood pressure, DPB diastolic blood pressure, HR heart rate, GHBA1C glycated hemoglobin A1c, TC total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, WBC white blood cell count, Hb hemoglobin, PLT platelet count, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, Neu neutrophils, Lym lymphocyte, Neu% percentage of Neu, Lym% percentage of Lym, CK creatine kinase, LDH lactate dehydrogenase, CK-MB creatine kinase Isoenzyme, Mb myoglobin, UMALB urinary albumin excretion, BUN urea, Scr serum creatinine, UA uric acid, HGI hemoglobin glycation index, TyG index triglyceride-glucose index, TG/HDL ratio triacylglycerol to high density lipoprotein cholesterol ratio, HOMA-IR homeostatic model assessment of insulin resistance, IGI insulinogenic index, IGI/HOMA-IR IGI to HOMA-IR ratio, HOMA-BETA homeostasis model of assessment for beta-cell function, I/G 0 min fasting insulin to glucose ratio, I/G 120 min 120 min insulin to glucose ratio, eGFR estimated glomerular filtration rate, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, CKD chronic kidney disease, DR diabetic retinopathy, DN diabetic neuropathy, CAD coronary artery disease, MI myocardial infarction, HT hypertension, ACCI age-adjusted Charlson comorbidity index, FRS Framingham risk score.
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