Figure 3

(A) Serum biomarker concentration profiles. Individual patient’s biomarker concentrations of serum (a) creatinine, (b) cystatin C, (c) CK and (d) Total Protein are shown [black dotted line—No AKI (alive (n = 34)), red dotted line—death (n = 1), green dotted line—AKIN1 (alive (n = 18)), purple dotted line—AKIN2 (alive (n = 5)) and brown dotted line—AKIN3 (alive (n = 1))]. The grey color shaded area illustrates 5th–75th percentile and light grey color shaded area indicates 75th–95th percentile of the normal range based on measurements in healthy individuals. (B) Changes in serum biomarker concentrations. Median and inter quartile ranges (IQRs) of the biomarker concentrations of serum (a) creatinine, (b) cystatin C, (c) CK and (d) Total Protein at different time interval are shown [black line—No AKI (alive n = 34, death n = 1), Red line—AKIN1/2/3 (alive n = 24, death n = 5)]. The grey colour shaded area illustrates 5th–75th percentile and light grey color shaded area indicates 75th–95th percentile of the normal range based on measurements in healthy individuals.