Table 5 Association of polymorphic variants with RILA values.

From: Association of polymorphisms in TGFB1, XRCC1, XRCC3 genes and CD8 T-lymphocyte apoptosis with adverse effect of radiotherapy for prostate cancer

Polymorphism

Genotype (No of patients): Mean value late GU toxicity RILA

ANOVA

Genotype (No of patients): Mean value late GI toxicity RILA

ANOVA

TGFB1

C-509T

CC (26): 33.8

CT (17): 27.7

TT (5): 43.0

p = 0.080

CC (12): 32.4

CT (5): 31.4

TT (2): 57.8

p = 0.055

TGFB1 Leu10Pro

LeuLeu (14): 34.4

LeuPro (24): 29.9

ProPro (8): 35.4

p = 0.522

LeuLeu (6): 33.5

LeuPro (10): 30.3

ProPro (2): 57.8

p = 0.050

XRCC1 Arg280His

NA

NA

NA

NA

XRCC3 Thr241Met

ThrThr (21): 32.5

ThrMet (18): 35.1

MetMet (7): 27.1

p = 0.438

ThrThr (7): 32.7

ThrMet (9): 40.2

MetMet (2): 27.5

p = 0.422

  1. NA- not applicable.
  2. Bolded values indicate statistically significant data or statistical trend.
  3. GU- genitourinary; GI- gastrointestinal.