Figure 3

Serum N-glycan differences between benign, DCIS, and invasive samples. Log-transformed relative intensity values of the (a) 2179.738 m/z (A2BG2S1) and (b) 2413.812 m/z (A2G2F1S2) N-glycans had significant differences in benign and DCIS samples using a 5% false discovery rate. (c) Using the log-transformed relative intensities of these N-glycans, age, BMI, and ethnicity/race, benign and DCIS samples could be distinguished with an AUROC of 0.732, and benign and invasive samples could be distinguished with an AUROC of 0.613. N-glycan compositions are represented by blue squares for N-acetylglucosamine, green circles for mannose, yellow circles for galactose, purple diamonds for sialic acid, and red triangles for fucose.