Table 1 Baseline characteristics, common primary problem, and blood test results.

From: Risk factors associated with cytomegalovirus reactivation in patients receiving immunosuppressive therapy for rheumatic diseases: a retrospective study

 

CMV-positive patients (n = 85)

CMV-negative patients (n = 387)

p value

Baseline characteristics and common primary problem

Age, mean ± SD, years

71.2 ± 15.1

64.4 ± 18.4

0.0022

Female, n (%)

65 (76.4%)

267 (69.0%)

0.0290

Duration between maximum dose of PSL and C7-HRP measurement, mean ± SD, days

263.5 ± 944.6

535.8 ± 1360.0

0.2228

Microscopic polyangiitis, n (%)

18 (21.2%)

15 (3.9%)

< 0.0001

Rheumatoid arthritis, n (%)

16 (18.8%)

131 (33.9%)

0.0009

Systemic lupus erythematosus, n (%)

14 (16.5%)

53 (13.7%)

0.0761

Adult-onset Still’s disease, n (%)

6 (7.1%)

5 (1.3%)

0.0002

Dermatomyositis, n (%)

4 (4.7%)

17 (4.4%)

0.1026

Eosinophilic granulomatosis with polyangiitis, n (%)

4 (4.7%)

12 (3.1%)

0.0706

Systemic sclerosis, n (%)

4 (4.7%)

8 (2.1%)

0.0273

Sjogren’s syndrome, n (%)

2 (2.4%)

23 (5.9%)

0.0305

Takayasu arteritis, n (%)

2 (2.4%)

7 (1.8%)

0.0959

Granulomatosis with polyangiitis, n (%)

2 (2.4%)

4 (1.0%)

0.0530

Anti-synthetase syndrome, n (%)

2 (2.4%)

4 (1.0%)

0.0530

Mixed connective tissue disease, n (%)

2 (2.4%)

4 (1.0%)

0.0530

Polymyalgia rheumatica, n (%)

1 (1.2%)

27 (7.0%)

0.0065

Proliferative nephritis, n (%)

1 (1.2%)

13 (3.4%)

0.0467

Behcet’s disease, n (%)

1 (1.2%)

13 (3.4%)

0.0467

Giant cell arteritis, n (%)

1 (1.2%)

9 (2.3%)

0.0759

IgG4-related disease, n (%)

1 (1.2%)

7 (1.8%)

0.0921

Polymyositis, n (%)

1 (1.2%)

4 (1.0%)

0.1027

Malignant rheumatoid arthritis, n (%)

1 (1.2%)

2 (0.5%)

0.0740

Blood test results

White blood cell count, mean ± SD, /µL

9260 ± 5190

8580 ± 4900

0.0001

Neutrophil count, mean ± SD, /μL

7720 ± 4660

6440 ± 4040

0.0001

Lymphocyte count, mean ± SD, /μL

820 ± 660

1190 ± 980

< 0.0001

Hemoglobin level, mean ± SD, g/dL

10.4 ± 2.1

11.1 ± 2.3

< 0.0001

Platelet count, mean ± SD, /μL

233,000 ± 125,000

259,000 ± 119,000

0.0002

Albumin level, mean ± SD, g/dL

2.9 ± 0.6

3.4 ± 0.8

0.0104

Creatinine level, mean ± SD, mg/dL

1.2 ± 1.0

0.9 ± 0.6

0.0026