Figure 1

Heatmap with notable microbially-derived gene ontology functional annotations associated with COVID-19 (n =32), as compared to community acquired pneumonia (n = 29) & uninfected (n=25) cohorts. Cells are colored via z-scale calculations of the total read counts for each GO term by sample. Rows are sorted by parental GO terms (depth = 1), and columns are clustered by Euclidean distance using ward D2 clustering. Comparisons were conducted using MaAsLin2, controlling for publication and patient ID with Benjamini Hochberg multiple test comparison (q < 0.05).