Table 3 Comparison of modified amino acids at specific sites in G6PDH and 6PGDH mediated by AAPH-derived ROO·.
G6PDH | 6PGDH | ||
|---|---|---|---|
Residue | % modification | Residue | % modification |
Methionine | Methionine | ||
M70 | High | M11 | High |
M105 | High | M14 | High |
M119 | High | M73 | High |
M235 | High | M141 | High |
M246 | High | M184 | High |
M249 | High | M194 | High |
M429 | High | Trp | |
M458 | High | W222 | High |
Tryptophan | W265 | High | |
W53 | High | W349 | High |
W79 | High | Tyrosine | |
W201 | High | Y27 | Low |
W223 | High | Y55 | Low |
W326 | High | Y90 | Low |
W328 | High | Y149 | High |
W364 | High | Y172 | Low |
W446 | High | Y230 | High |
W448 | High | Y248 | Low |
W456 | High | Y333 | Low |
Tyrosine | Y353 | Low | |
Y31 | Low | Y378 | Low |
Y116 | Low | Y392 | Low |
Y288 | Low | Y400 | Low |
Y301 | Low | Histidine | |
Y351 | Low | H180 | Low |
Y408 | Low | ||
Histidine | |||
H416 | Low | ||
