Figure 1

Exemplary images from a report of a SPG4 patient to control the automated segmentation results. These representative images were taken from an AIRAscore structure report of a SPG4 patient (#11) which can be used for quality control of the segmentation process. In (A) the segmentation results show the gray matter (in red) and the white matter (in blue) in transversal, coronal, and sagittal planes. In (B) the anatomical labels of the specified brain lobes are shown: frontal (green), parietal (blue), temporal (red), occipital (brown), and insula (lilac). Additional regions are also labeled the midbrain (orange), pons (turquoise), cingulate gyrus (yellow), hippocampus (grey), the ventricles (purple), and the cerebellum (darker turquoise).