Figure 2 | Scientific Reports

Figure 2

From: Proof of principle for the clinical use of a CE-certified automatic imaging analysis tool in rare diseases studying hereditary spastic paraplegia type 4 (SPG4)

Figure 2

Scoring diagram of all percentile values of the SPG4 cohort and their age- and gender-matched controls are shown with their age dependency. All percentile values (y-axis) of the SPG4 patients (filled black dots) and the controls (unfilled dots) are shown together with the respective age of the individual (x-axis) for representative brain region: (A) Total brain, (B) White matter, (C) Gray matter, (D) Midbrain, (E) Pons, (F) Hippocampus bilateral, (G) Cingulate gyrus bilateral, (H) Lateral ventricles, and (I) Third ventricle. In all of these shown areas but Gray matter in (C) were significant group differences (compare Table 2). Linear fits are shown for the controls (dotted line) and the SPG4 patients (black line).

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