Table 1 Demographics of the analyzed SPG4 cohort and sex- and age-matched controls.

From: Proof of principle for the clinical use of a CE-certified automatic imaging analysis tool in rare diseases studying hereditary spastic paraplegia type 4 (SPG4)

 

Healthy controls (n = 24)

SPG4 patients (n = 24)

p-values

Gender

♀

11

11

1.0

♂

13

13

Age [years]

49.8 (11.59)

50.4 (11.52)

0.852

Disease duration [years]$

n/a

15.0$ {19.0}

 

SPRS total score$

n/a

20.5$ {21}

 
  1. Presented are demographics as well as standardized disease parameters of the SPG4 patients and their age- and gender matched controls. Gaussian distribution of parameters was assessed using the Shapiro–Wilk-Test. Age as Gaussian distributed variable was compared by a two-sided t-test, disease duration and total SPRS score (non-Gaussian distributed variable) were tested using the Mann–Whitney-U test, and gender as nominal variable with chi square test. Gaussian distributed data is presented as mean (standard deviation) and non-gaussian distributed data (as median$ {interquartile range}.
  2. Significant values are in bold.
  3. $Non-gaussian distributed variable, n/a not applicable.
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