Table 4 Ocular symptoms and signs according to season.

From: Seasonal variations in presenting symptoms and signs of dry eye disease in Norway

 

Spring

Summer

Fall

Winter

P-value

Ocular surface disease index

36.7 ± 22.3

31.6 ± 19.4

35.4 ± 20.4

35.1 ± 21.5

0.51a

Dry eye severity level

2.0 ± 0.4

2.1 ± 0.5

2.0 ± 0.5

2.0 ± 0.5

0.85a

Dry eye severity level 1 (% within season)

8.5

10.2

10.2

10

Dry eye severity level 2 (% within season)

81.5

71.4

75.8

75.4

Dry eye severity level 3 (% within season)

9.5

18.4

14

14.7

Dry eye severity level 4 (% within season)

0.5

0

0

0

Tear film breakup time

5.0 ± 3.9

6.7 ± 10.1

5.6 ± 3.9

4.9 ± 3.9

0.34a

Ocular protection index

2.1 ± 2.2

2.7 ± 2.6

2.0 ± 1.6

1.8 ± 1.7

0.06a

Ocular surface staining

1.5 ± 2.0

1.6 ± 2.2

1.5 ± 2.0

1.7 ± 2.1

0.67a

Schirmer I

16.1 ± 10.5

10.1 ± 7.5b

15.8 ± 10.3

15.4 ± 10.3

0.002a

Tear meniscus height (% < 0.2 mm)

11.9

16.0

29.2d

8.7

< 0.001c

Meibum expressibility

1.1 ± 0.9

0.7 ± 0.8

1.0 ± 0.9

1.0 ± 0.9

0.051a

Intraocular pressure

13.9 ± 3.2

12.9 ± 2.4

13.1 ± 3.6

15.1 ± 3.7e

< 0.001a

  1. aOne-way analysis of variance; bP < 0.01 compared to all other seasons (Tukey post hoc test); cChi-square test; dhigher percentage than expected (P < 0.001; Chi-square test); eP < 0.05 compared to summer and fall (Tukey post hoc test); Bold font = statistically significant.