Figure 5
Evaluation of the Ca2+-transients after application of 10 mM caffeine. The step-by-step increasing Ca2+ transients (panel a) reached their steady-state value after the 10th stimulus where the diastolic Ca2+ transient (panel b) was not changed while the transient amplitude (panel c) was higher in the presence of 8 mM pipette NaCl (red graphs). The bar graph in panel (c) indicates faster change of transient amplitude between 1st and 2nd beats when pipette Na+ was adjusted to 8 mM while in the case of diastolic Ca2+ level it was found identical refilling kinetics between 2 (blue column) and 8 (red column) pipette NaCl (bar graph, panel b). Independent t-test, *means p < 0.05.
