Table 5 Multivariate logistic regression model for predicting recovery from ISSNHL.

From: Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis

Independent variable

Adjusted OR

95% CI

p-value

Age

 　< 60

1

(Reference)

 

　 ≥ 60

1.32

0.92 to 1.88

0.13

DM

0.83

0.53 to 1.29

0.41

HTN

0.60

0.41 to 0.87

 < 0.01**

HLD

0.83

0.56 to 1.24

0.37

V/D

2.54

1.72 to 3.75

 < 0.01***

Initial MHLWa Grade of hearing loss, affected ear

　1–3

1

(Reference)

 

　4

3.42

1.84 to 6.35

 < 0.01***

Initial Grade of hearing loss, healthy ear

　0–1

1

(Reference)

 

　2–4

1.89

1.09 to 3.29

0.02*

Hearing loss

　Low frequencies

1.35

0.84 to 2.19

0.22

　Middle frequencies

1.53

0.76 to 3.09

0.23

　High frequencies

1.86

1.13 to 3.06

0.01*

Regular anticoagulant medication at onset of hearing loss

3.37

1.17 to 9.73

0.02*

Received systemic steroid therapy, yes

1.24

0.56 to 2.74

0.60

Received intratympanic steroid therapy (initial or salvage), yes

0.70

0.34 to 1.41

0.32

Latency to begin steroid treatmentc

　0–7 days post-onset

1

(Reference)

 

　8 or more days post-onset

2.85

1.77 to 4.59

 < 0.01***

Received prostaglandin E1 treatment, yes

0.83

0.54 to 1.27

0.38

  1. Same abbreviations as in Table 1.
  2. Dependent variable = no recovery.
  3. OR, odds ratio; CI, confidence interval.
  4. *p < 0.05, ** p < 0.01, ***p < 0.001.
  5. aCriteria of the Sudden Deafness Research Committee of the Ministry of Health, Labour and Welfare.
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