Table 3 Regression coefficients obtained through linear regression models for PWV values.

From: Sclerostin as a biomarker of cardiovascular risk in women with systemic lupus erythematosus

Variable

Crude estimates

Adjusted estimatesa

Predictive modelb

Coeff

95% CI

Coeff

95% CI

Coeff

95% CI

Sclerostinc

0.14

0.08; 0.20

− 0.03

− 0.06; 0.00

  

Age

0.10

0.09; 0.11

0.08

0.06; 0.10

0.08

0.07; 0.09

BMI

0.11

0.05; 0.16

− 0.01

− 0.04; 0.02

  

SLE duration

0.06

0.03; 0.10

0.02

− 0.00; 0.03

  

Smoking

0.44

− 0.27; 1.15

0.16

− 0.18; 0.50

  

Sedentary

0.49

− 0.11; 1.08

− 0.04

− 0.29; 0.21

  

HTN

1.05

0.49; 1.61

0.35

0.10; 0.60

0.29

0.08; 0.51

LDL ≥ 130 mg/dL

0.88

0.29; 1.48

− 0.13

− 0.41; 0.14

  

MetS

1.33

0.60; 2.05

0.33

− 0.11; 0.78

  

SLEDAI-SELEN

− 0.15

− 0.30; − 0.02

0.00

− 0.06; 0.06

  

SDI > 0

− 0.10

− 0.81; 0.62

0.04

− 0.23; 0.30

  

APS

0.29

− 0.77; 1.36

0.13

− 0.26; 0.52

  

Prednisone

− 0.02

− 0.25; 0.22

0.06

− 0.04; 0.16

  

HCQ use

− 0.34

− 1.19; 0.52

− 0.38

− 0.72; − 0.04

  

LN

− 0.61

− 1.20; − 0.01

− 0.39

− 0.71; − 0.06

  

CPR

0.03

− 0.02; 0.07

− 0.03

− 0.05; − 0.01

− 0.02

− 0.04; − 0.01

C3

0.02

0.01; 0.03

− 0.00

− 0.01; 0.01

  

C4

0.04

− 0.01; 0.09

0.02

− 0.01; 0.04

  

Framingham

0.39

0.33; 0.46

0.10

0.03; 0.17

0.12

0.07; 0.18

  1. BMI body mass index, HTN hypertension, LDL low density lipoprotein, MetS metabolic syndrome, SLEDAI-SELENA Systemic Lupus Erythematosus Disease Activity Index, SDI Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index, APS antiphospholipid syndrome, HCQ hydroxychloroquine, LN lupus nephritis.
  2. aThe model included all the independent variables shown in the table.
  3. bThe stepwise model included only variables with a p-to-enter value < 0.05 and a p-to-remove value > 0.10.
  4. cEstimated for sclerostin value × 10.