Figure 2 | Scientific Reports

Figure 2

From: The mutational spectrum in whole exon of p53 in oral squamous cell carcinoma and its clinical implications

Figure 2

Immunohistological evaluation of p53 in oral squamous cell carcinoma (OSCC) cases. No abnormal accumulation of p53 protein in the nucleus was observed in cases in which no mutation was found by next-generation sequencing (NGS) (A,D). In cases with a mutation detected by NGS, abnormal nuclear accumulation of p53 protein was found immunohistologically (B,E). In cases with a truncation mutation detected by NGS, the absence of abnormal nuclear accumulation of p53 protein was shown immunohistologically (C,F).

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