Table 1 Characteristics of the patients and the p53 mutational spectrum.
|  | n = 67 (cases) | Missense mutation | Truncation mutation | Wild-type/p16 +  | Wild-type/p16- |
|---|---|---|---|---|---|
Age | |||||
< 65 years | 25 | 9 | 14 | 2 | 0 |
≥ 65 years | 42 | 22 | 9 | 4 | 7 |
Gender | |||||
Male | 39 | 18 | 15 | 5 | 1 |
Female | 28 | 13 | 8 | 1 | 6 |
Smoking | |||||
Smoking | 34 | 16 | 12 | 5 | 1 |
Non smoking | 33 | 15 | 11 | 1 | 6 |
Drinking | |||||
Drinking | 30 | 14 | 10 | 4 | 2 |
Non drinking | 37 | 17 | 13 | 2 | 5 |
UICC pathological T category | |||||
pT1 | 8 | 5 | 1 | 1 | 1 |
pT2 | 21 | 9 | 8 | 1 | 3 |
pT3 | 15 | 6 | 7 | 2 | 0 |
pT4a | 17 | 9 | 5 | 1 | 2 |
pT4b | 6 | 2 | 2 | 1 | 1 |
UICC pathological N category | |||||
pN0 | 39 | 18 | 9 | 5 | 7 |
pN1 | 13 | 7 | 5 | 1 | 0 |
pN2a | 5 | 3 | 2 | 0 | 0 |
pN2b | 7 | 1 | 6 | 0 | 0 |
pN2c | 2 | 1 | 1 | 0 | 0 |
pN3a | 0 | 0 | 0 | 0 | 0 |
pN3b | 1 | 1 | 0 | 0 | 0 |
UICC pathological stage | |||||
Stage I | 8 | 5 | 1 | 1 | 1 |
Stage II | 13 | 5 | 5 | 0 | 3 |
Stage III | 18 | 10 | 5 | 3 | 0 |
Stage IVa | 22 | 9 | 10 | 1 | 2 |
Stage IVb | 6 | 2 | 2 | 1 | 1 |
Tumor cell differentiation | |||||
Well | 29 | 12 | 9 | 4 | 4 |
Moderate | 19 | 10 | 6 | 1 | 2 |
Poor | 19 | 9 | 8 | 1 | 1 |
Y–K mode of invasion | |||||
1 | 9 | 5 | 1 | 1 | 2 |
2 | 14 | 6 | 3 | 2 | 3 |
3 | 28 | 15 | 12 | 0 | 1 |
4C | 15 | 4 | 7 | 3 | 1 |
4D | 1 | 1 | 0 | 0 | 0 |
