Figure 6

Identification prognosis-related differentially expressed microRNAs and conduction of the ceRNA regulation network under hypoxic status. (A) Volcano plot for differentially expressed microRNAs in cluster1 and cluster2. Red and green dots represent up-regulated and down-regulated in cluster1 relative to cluster2, respectively (P < 0.01, |logFC|> 1). (B–D) The overall survival curves of hsa-miR-196b, hsa-miR-31, hsa-miR-9 in TCGA-LUAD. (E) Venn diagrams showing the intersection between predicted target genes of hsa-miR-196b/hsa-miR-31/hsa-miR-9 and DEGs. (F–L) The overall survival curves of PCSK2, FREM2, ALPL, ATP1A2, CEBPA in TCGA-LUAD. (K) The microRNA-lncRNA networks of the target lncRNAs of hsa-miR-196b, hsa-miR-31 and hsa-miR-9. (L) The ceRNA regulation network based on differentially expressed microRNAs and DEGs under hypoxic status.